BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM (BPDCN)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy derived from plasmacytoid dendritic cell precursors with skin, lymph node, blood, central nervous system (CNS), and bone marrow involvement.8 While BPDCN is currently considered a unique myeloid neoplasm, it had previously been classified as a subset of acute myeloid lymphoma (AML).9
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy derived from plasmacytoid dendritic cell precursors with skin, lymph node, blood, central nervous system (CNS), and bone marrow involvement.8 While BPDCN is currently considered a unique myeloid neoplasm, it had previously been classified as a subset of acute myeloid lymphoma (AML).9
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy derived from plasmacytoid dendritic cell precursors with skin, lymph node, blood, central nervous system (CNS), and bone marrow involvement.8 While BPDCN is currently considered a unique myeloid neoplasm, it had previously been classified as a subset of acute myeloid lymphoma (AML).9
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy derived from plasmacytoid dendritic cell precursors with skin, lymph node, blood, central nervous system (CNS), and bone marrow involvement.8 While BPDCN is currently considered a unique myeloid neoplasm, it had previously been classified as a subset of acute myeloid lymphoma (AML).9
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy derived from plasmacytoid dendritic cell precursors with skin, lymph node, blood, central nervous system (CNS), and bone marrow involvement.8 While BPDCN is currently considered a unique myeloid neoplasm, it had previously been classified as a subset of acute myeloid lymphoma (AML).9
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- Pemmaraju N, Deconinck E, Mehta P, et al: Recent advances in the biology and CD123-directed treatment of blastic plasmacytoid dendritic cell neoplasm. Clin Lymphoma Myeloma Leuk 24:e130-e137, 2024.