Research Approaches

Investing in New Technologies & Approaches

Cancer treatment is evolving as researchers continue to reveal the intricacies of cancer pathology and leverage this knowledge to discover novel therapeutic approaches. AbbVie is committed to leading the advancement of cancer treatment by pursuing innovative research technologies driven by our deep understanding of oncogenic pathways and biomarkers.

Core Areas of Biology

Technologies

  1. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-674.
  2. Finn OJ. Immuno-oncology: understanding the function and dysfunction of the immune system in cancer. Ann Oncol. 2012;23(suppl8):viii6-viii9.
  3. Aponte PM, Caicedo A. Stemness in cancer: stem cells, cancer stem cells, and their microenvironment. Stem Cell International. 2017.
  4. Fan G, Wang Z, Hao M, Li J. Bispecific antibodies and their applications. J Hematol Oncol. 2015;8:130. Doi:10.1186/s13045-015-0227-0.
  5. Peters C, Brown S. Antibody-drug conjugates as novel anti-cancer chemotherapeutics. Biosci Rep. 2015;35(4):e00225.
  6. Diamantis N, Banerji U. Antibody-drug conjugates—an emerging class of cancer treatment. Br J Cancer. 2016;114(4):362-367.
  7. Hoelder S, et al. Discovery of small molecule cancer drugs: successes, challenges and opportunities. Mol Oncol. 2012;6(2):155-76.

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